Sleep Apnea, Norepinephrine-Release Rate, and Daytime Hypertension

Sleep apnea and hypertension.

Obstructive sleep apnea and hypertension.

There has long been a recognized link between obstructive sleep apnea (OSA) and the cardiovascular system, no aspect of which has been more studied than blood pressure. Research in OSA has not only demonstrated dysregulation of homeostatic cardiovascular mechanisms but also has furthered our understanding of blood pressure regulatory control. Acute nocturnal blood pressure elevations associated...

Hypertension and obstructive sleep apnea

Obstructive sleep apnea (OSA) is increasingly being recognized as a major health burden with strong focus on the associated cardiovascular risk. Studies from the last two decades have provided strong evidence for a causal role of OSA in the development of systemic hypertension. The acute physiological changes that occur during apnea promote nocturnal hypertension and may lead to the development...

Obesity, sleep apnea, and hypertension.

Obesity has a high and rising prevalence and represents a major public health problem. Obstructive sleep apnea (OSA) is also common, affecting an estimated 15 million Americans, with a prevalence that is probably also rising as a consequence of increasing obesity. Epidemiologic data support a link between obesity and hypertension as well as between OSA and hypertension. For example, untreated O...

Hypertension, sleep apnea, and atherosclerosis.

Having obstructive sleep apnea (OSA) increases the relative odds of also having coronary artery disease by 27% and of having suffered a stroke by 58%.1 Approximately 50% of individuals with OSA are also hypertensive, and those who are not initially so have an 3-fold increase in their likelihood of developing hypertension after 4 years if their apnea-hypopnea index (AHI) is 15 events per hour.2–...